Image: Northwest Fisheries Science Center | Strong Genomic and Phenotypic Heterogeneity in the Aeromonas sobria Species Complex Jeff Gauthier, Antony T. Vincent, Steve J. Charette and Nicolas Derome Front. Microbiol., 08 December 2017 Aeromonas sobria is a mesophilic motile aeromonad for which, despite increasing evidence of mutualistic interactions in salmonid fish, the determinants of its host-microbe associations remain poorly understood. The ongoing confusion between A. sobria (sensu stricto) and A. veronii bv. sobria further increases this knowledge gap. In this new publication, we assessed the genomic and phenotypic heterogeneity among five A. sobria strains. Two clinical isolates recovered from infected fish (JF2635 and CECT 4245), one from an infected amphibian (08005) and two recently isolated brook charr probionts (TM12 and TM18) which inhibit in vitro growth of A. salmonicida subsp. salmonicida (a salmonid fish pathogen). [To read the article click here] |
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-- Learn more about the Sentinel North Research Strategy below -- Northern ecosystems are facing unprecedented assaults resulting from direct (e.g. industrial activities, such as mining and hydroelectricity) and indirect (global warming) anthropogenic activities, thus amplifying the risk of disturbing essential ecosystem services mediated by microbial communities (nitrogen cycle, primary production) and contaminate the whole food web. Because gut microbiota is critically implicated in modulating the host response to contaminants and toxins, such bio-accumulated contaminants (e.g. iron, mercury, arsenic, lead, cadmium, arsenic and manganese) are expected to have serious consequences on major host functions such as immune response, energetic performance and development. Furthermore, there are enough results suggesting that climate change could alter stages and rates of development of endemic pathogens, modify host resistance, and result in changes in the physiology of host-pathogen interactions. Because microbiota constitutes the first immune barrier by both producing specific antimicrobial compounds and outcompete invasive microbes for host resources, it is crucial to develop a sentinel model for studying skin and gut microbiota resilience when facing allochthonous pathogens in controlled conditions.
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