Walleye Autochthonous Bacteria as Promising Probiotic Candidates against Flavobacterium columnare
Hamza Seghouani, Carlos Enrique Garcia Rangel, Jérémie Füller, Jeff Gauthier and Nicolas Derome
Frontiers in Microbiology / Aquatic Microbiology, 18 July 2017
In this publication, we report two novel Pseudomonas fluorescens strains isolated from the walleye gut microbiota. Those two strains improved by 54% the survival of walleye juveniles infected by Flavobacterium columnare, a major opportunistic pathogen of walleye and salmonid fish.
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Northern ecosystems are facing unprecedented assaults resulting from direct (e.g. industrial activities, such as mining and hydroelectricity) and indirect (global warming) anthropogenic activities, thus amplifying the risk of disturbing essential ecosystem services mediated by microbial communities (nitrogen cycle, primary production) and contaminate the whole food web. Because gut microbiota is critically implicated in modulating the host response to contaminants and toxins, such bio-accumulated contaminants (e.g. iron, mercury, arsenic, lead, cadmium, arsenic and manganese) are expected to have serious consequences on major host functions such as immune response, energetic performance and development. Furthermore, there are enough results suggesting that climate change could alter stages and rates of development of endemic pathogens, modify host resistance, and result in changes in the physiology of host-pathogen interactions. Because microbiota constitutes the first immune barrier by both producing specific antimicrobial compounds and outcompete invasive microbes for host resources, it is crucial to develop a sentinel model for studying skin and gut microbiota resilience when facing allochthonous pathogens in controlled conditions.