DEROME LABORATORY
  • News
  • Work with us
    • PhD - Aug 2019 - ZEBRIGHTmicro
    • PhD - Aug 2019 - BeeProbio 3
  • Team
    • Nicolas Derome - Principal Investigator
    • Pierre-Luc Mercier - Research Professional
    • Bachar Cheaib - Ph.D. Student
    • Sarah El Khoury - Ph.D. Student
    • Jeff Gauthier - Ph.D. Student
    • François-Étienne Sylvain - Ph.D. Student
    • Flora Amill - Ph.D. Student
    • Hamza Seghouani - MSc Student
    • Laurence Auger - MSc Student
    • Sidki Bouslama - MSc Student
  • Alumni
    • Camille Lavoie - MSc Student
    • Amine Chaabane - M2 Student
    • Sébastien Boutin, Ph.D.
    • Martin Llewellyn, Ph.D.
    • Florian Thonier, M2
  • Publications
  • Links
  • Contact

NEW PhD Research Opportunities @ Derome Lab

6/21/2019

0 Comments

 
Picture
The Derome Laboratory has an exceptional opportunity available for two PhD students to join our research team:
  1. Project BeeProbio3: High throughput and integrative insect model to model the interplay of stress factors controlling host-microbiota interactions at the interface of health/disease.
  2. Project ZEBRIGHTmicro: Optimizing an instant, high throughput and integrative vertebrate model to decipher the interplay of factors controlling host-microbiota interactions along development at the interface of health/disease.
Candidates must apply before Aug 30th, 2019 (send CV, cover letter and two letters of support to nicolas.derome@bio.ulaval.ca). More information in the "Work with us" section or the links above.
0 Comments

New Book: Microbial Communities in Aquaculture Ecosystems

6/14/2019

0 Comments

 
Picture
A new collaborative textbook, edited by Nicolas Derome, has now been published in Springer Nature:
  • Microbial Communities in Aquaculture Ecosystems: Improving productivity and sustainability
It overviews state-of-the-art knowledge on free-living and host-associated microbiota and their importance on both fish health and the long-term sustainability of fish farming.
It also addresses high throughput techniques to monitor those host-microbiota interactions. Applications that resulted from microbiota monitoring studies (e.g. improve water quality, prevent opportunistic infections and improving fish performance) are also discussed.
0 Comments

New PhD Position - Black Soldier Fly Microbiomics

2/8/2019

0 Comments

 
Picture
Goal: Developing an instant, high throughput and integrative insect larvae model to decipher the interplay of factors controlling host-microbiota interactions for biotransforming waste biomass into high value biochemicals. 
​
 Skills: Background in molecular biology and bioinformatics, excellent communication and teamwork skills. Salary: CAD $21,000 per year, for 3 years.

[ THIS OFFER IS NOW CLOSED. ]
0 Comments

New Publication

8/7/2018

0 Comments

 
Picture
Picture
A brief history of bioinformatics
Jeff Gauthier, Antony T. Vincent, Steve J Charette and Nicolas Derome
​
Briefings in Bioinformatics | https://doi.org/10.1093/bib/bby063

To access the article, click here.
(for personal use only, do not redistribute this link)
Here we present an integrative timeline of key events in bioinformatics and related fields during the past half-century, as well as some background on parallel advances in molecular biology and computer science, and some reflections on the future of bioinformatics.
0 Comments

Team Highlights - Sentinel North Scholarship

5/14/2018

0 Comments

 
Picture
Picture
Congratulations to Amine Chaabane, who was awarded a Sentinel North scholarship for international graduate students.
Through this program, Sentinel North seeks to attract new talent, foster the development of young international scientists able to tackle and help resolve complex northern issues, and encourage the sharing of knowledge and experience across borders.
Amine's project aims to study two populations of Arctic char (Salvelinus alpinus) from the North region of Canada and trying to observe the impact of climate change and physiological parameters differences on this microbiota.
For more information about the Sentinel North international scholarship program, click here.
0 Comments

New Publication

5/12/2018

0 Comments

 
Picture
Deleterious interaction between honeybees (Apis mellifera) and its microsporidian intracellular parasite Nosema ceranae was mitigated by administrating either endogenous or allochthonous gut microbiota strains.

Sarah El Khoury, Nicolas Derome, Pierre Giovenazzo, Andrée Rousseau, Alexandre Lecoeur, Pierre-Luc Mercier,  Bachar Cheaib, Sidki Bouslama, Vanessa Demey and Mathieu Castex

Frontiers in Ecology and Evolution | doi: 10.3389/fevo.2018.00058
(Full-text will be available on Frontiers soon)

ABSTRACT: Honey bees (Apis mellifera) are facing multiple stressors affecting their lifespan, health and productivity. Among them, Nosema ceranae is an intracellular microsporidian parasite, which plays a major impact on honey bees colonies. However, both efficiency and innocuity of current treatment against N. ceranae are observed, thus raising the urgent need to develop alternative prophylactic and curative strategies. Endogenous microbial...

Read More
0 Comments

New Publication in Frontiers

5/9/2018

0 Comments

 
Picture
Picture
Source: USGS // Public Domain.
Taxon-Function Decoupling as an Adaptive Signature of Lake Microbial Metacommunities Under a Chronic Polymetallic Pollution Gradient
Bachar Cheaib, Malo Le Boulch, Pierre-Luc Mercier et Nicolas Derome
Frontiers in Microbiology // 03 May 2018

Abstract: Adaptation of microbial communities to anthropogenic stressors can lead to reductions in microbial diversity and disequilibrium of ecosystem services. Such adaptation can change the molecular signatures of communities with differences in taxonomic and functional composition. Understanding the relationship between taxonomic and functional variation remains a critical issue in microbial ecology. Here, we assessed the taxonomic and functional diversity of a lake metacommunity system along a polymetallic pollution gradient caused by 60 years of chronic exposure to acid mine drainage (AMD). Our results highlight three adaptive signatures. First, a signature of taxon—function decoupling was detected in the microbial communities of moderately and highly polluted lakes. Second, parallel shifts in taxonomic composition occurred between polluted and unpolluted lakes. Third, variation in the abundance of functional modules suggested a gradual deterioration of ecosystem services (i.e., photosynthesis) and secondary metabolism in highly polluted lakes. Overall, changes in the abundance of taxa, function, and more importantly the polymetallic resistance genes such as copA, copB, czcA, cadR, cCusA, were correlated with trace metal content (mainly Cadmium) and acidity. Our findings highlight the impact of polymetallic pollution gradient at the lowest trophic levels.
0 Comments

New Publication in Front. Microbiol.

12/20/2017

0 Comments

 
Picture
Picture
Image: Northwest Fisheries Science Center
Strong Genomic and Phenotypic Heterogeneity in the Aeromonas sobria Species Complex
Jeff Gauthier, Antony T. Vincent, Steve J. Charette and Nicolas Derome
Front. Microbiol., 08 December 2017

Aeromonas sobria is a mesophilic motile aeromonad for which, despite increasing evidence of mutualistic interactions in salmonid fish, the determinants of its host-microbe associations remain poorly understood. The ongoing confusion between A. sobria (sensu stricto) and A. veronii bv. sobria further increases this knowledge gap.

In this new publication, we assessed the genomic and phenotypic heterogeneity among five A. sobria strains. Two clinical isolates recovered from infected fish (JF2635 and CECT 4245), one from an infected amphibian (08005) and two recently isolated brook charr probionts (TM12 and TM18) which inhibit in vitro growth of A. salmonicida subsp. salmonicida (a salmonid fish pathogen).

​[To read the article click here]
0 Comments

New Publication in Frontiers

7/18/2017

0 Comments

 
Picture
Image: NOAA // CC BY-SA
Walleye Autochthonous Bacteria as Promising Probiotic Candidates against Flavobacterium columnare
Hamza Seghouani, Carlos Enrique Garcia Rangel, Jérémie Füller, Jeff Gauthier and Nicolas Derome
Frontiers in Microbiology / Aquatic Microbiology, 18 July 2017

In this publication, we report two novel Pseudomonas fluorescens strains isolated from the walleye gut microbiota.  Those two strains improved by 54% the survival of walleye juveniles infected by Flavobacterium columnare, a major opportunistic pathogen of walleye and salmonid fish.

​(To view this article, click on the title above.)
0 Comments

New Publication in Scientific Reports

7/17/2017

0 Comments

 
Picture
Image: Magnus Manske // CC-BY 2.0 (2008)
Vertically and horizontally transmitted microbial symbionts shape the gut microbiota ontogenesis of a skin-mucus feeding discus fish progeny
Scientific Reports 7:5263 (2017)

This new publication, authored by François-Étienne Sylvain and Nicolas Derome, discusses the gut microbiota acquisition patterns in the Discus fish, which display a unique parenting behaviour by feeding their fry off their own skin mucus in the early life stages.

To read this article, click the link below:
https://www.nature.com/articles/s41598-017-05662-w
0 Comments
<<Previous

    Archives

    June 2019
    February 2019
    August 2018
    May 2018
    December 2017
    July 2017
    May 2017
    February 2017
    November 2016
    August 2016
    July 2016
    June 2016
    March 2016
    January 2016
    November 2015
    October 2015
    September 2015
    July 2015
    May 2015
    April 2015
    March 2015

    RSS Feed

    Webmaster

Ⓒ 2014-2019. Website by Jeff Gauthier.  All rights reserved to Derome Laboratory.